Kathleen Gallo
Ph.D., 1992, Harvard University
Professor, Departments of Physiology, Biochemistry, and Molecular Biologyy
gallok@msu.edu
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Research Interests
We recently identified a novel, intracellular human protein serine/threonine kinase SPRK that upon overexpression transforms cells and renders them competent to form tumors in nude mice. We are studying the role of SPRK and of other novel protein kinases in mammalian signal transduction and cancer.
Selected Publications
Search all publications in the NCBI Journal Database
Gallo, K.A., M.R. Mark, Z. Wang, D.T. Scadden, Q. Gu and P.J. Godowski. Identification and characterization of SPRK, a novel SH3 domain-containing proline-rich kinase with serine/threonine kinase activity. J. Biol. Chem. 269:15092-15100, 1994.
Gaudino, G., A. Follenzi, L. Naldini, C. Collesi, M. Santoro, K.A. Gallo, P.J. Godowski and P.M. Comoglio. Ron is a heterodimeric tyrosine kinase receptor activated by the HGR-homolog MSP. EMBO J. 13:3524-3532, 1994.
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