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photoKathleen Gallo

Ph.D., 1992, Harvard University
Professor, Departments of Physiology, Biochemistry, and Molecular Biologyy

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Research Interests

We recently identified a novel, intracellular human protein serine/threonine kinase SPRK that upon overexpression transforms cells and renders them competent to form tumors in nude mice. We are studying the role of SPRK and of other novel protein kinases in mammalian signal transduction and cancer.

Selected Publications

Search all publications in the NCBI Journal Database

Gallo, K.A., M.R. Mark, Z. Wang, D.T. Scadden, Q. Gu and P.J. Godowski. Identification and characterization of SPRK, a novel SH3 domain-containing proline-rich kinase with serine/threonine kinase activity. J. Biol. Chem. 269:15092-15100, 1994. 

Gaudino, G., A. Follenzi, L. Naldini, C. Collesi, M. Santoro, K.A. Gallo, P.J. Godowski and P.M. Comoglio. Ron is a heterodimeric tyrosine kinase receptor activated by the HGR-homolog MSP. EMBO J. 13:3524-3532, 1994.


 

 

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