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photoGerard L. Gebber

Ph.D., 1964, University of Michigan
Professor, Dept. Pharmacology & Toxicology

Research Interests

One of the least understood aspects of autonomic neurobiology concerns the central mechanisms responsible for the control of sympathetic nerve discharges. There is considerable data supporting the view that disturbances in control of autonomic nerve activity can contribute to the development or maintenance of hypertension, cardiac dysrhythmias, and other cardiovascular diseases. Recent work demonstrates that different rhythms are evident in sympathetic nerve activity depending upon the experimental conditions. The major objectives of the research in our laboratories are

  1. to determine which regions of the brain contain the neurons responsible for the different rhythms in sympathetic activity
  2. to identify the interconnections of single neurons with activity correlated to sympathetic nerve activity
  3. to determine what role the different rhythms play in regulating vasomotor tone and in mediating complex and highly differentiated cardiovascular response patterns as occur during defense,exercise, and sleep

Please feel free to contact me if you have any questions about my research.

Selected Publications

Search all publications in the NCBI Journal Database

Gebber GL, Orer HS, and Barman SM.  Fractal noises and motions in time series of presympathetic and sympathetic neural activities.  J Neurophysiol 95: 1176-1184, 2006.

Orer HS, Gebber GL, and Barman SM. Medullary lateral tegmental field neurons influence the timing and pattern of phrenic nerve activity in cats. J Appl Physiol 101: 521-530, 2006.

Gebber, GL, SM Barman, and Fadel PJ.  Fractal fluctuations in breath number, period, and amplitude are independently controlled in awake, healthy humans.  IEEE Conference Proceedings,  28: 4616-4618, 2006.


 

 

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