Research Interests
Prof. Oweiss is the founder and director of the Neural Systems Engineering Laboratory (NSEL) at MSU. The primary mission of NSEL is to engineer theoretical, computational, and experimental tools for basic neuroscience research and clinical applications. To achieve this mission, NSEL focuses on the emerging Neural Engineering area of science. This interdisciplinary area has witnessed revolutionary progress in the last few years, mainly attributed to striking advances in the engineering of measurement devices, processing algorithms, and sophisticated models of brain function at multiple temporal and spatial resolutions.
In the short term, Dr. Oweiss's lab focuses on Brain Machine Interface (BMI) technology, broadly defined to be a direct communication pathway between a human (or animal) brain (or cell culture) and a man-made device. The later can be a simple electrode, an active circuit on a silicon chip, or even a network of computers. With this technology, Dr. Oweiss's lab seeks to: 1) Improve our understanding of the neural basis for sensorimotor integration; 2) build adequate models of neuronal connectivity at multiple temporal and spatial scales, and validate these models experimentally; and 3) Quantify how the neural information processing mechanism may be altered in the pathological state and how it can be manipulated through interactions with these artificial devices with an ultimate goal to restore damaged human function such as hearing, sight and movement.
Over the long term, Dr. Oweiss's research seeks to integrate the developed models and the processing tools with systems biology to understand the role of molecular and genetic regulation mechanisms on neural regeneration, growth and connectivity at the single cell, population and network levels. Because of its interdisciplinary nature, research in the Oweiss lab builds heavily upon the fields of computational and experimental neuroscience, clinical neurology, signal processing, information theory, dynamic systems, materials science, and nanotechnology.
Website: www.oweisslab.org
Selected Publications
Search all publications in the NCBI Journal Database
K. G. Oweiss, D. J. Anderson, "Spike Superposition Resolution in Multichannel Extracellular Recordings: A Novel Approach," Handbook of Neural Engineering. ch 22, Edited by Metin Akay, pp. 369-381, IEEE/Wiley, 2007.
K. Oweiss, "A Systems Approach for data compression and latency reduction in cortically controlled brain machine interfaces," IEEE Transactions on Biomedical Engineering, vol. 53, no.7, pp. 1364 – 1377, July 2006.
K. Oweiss, R. Jin, Y. Suhail, “Identifying neuronal assemblies with local and global connectivity with spectral clustering in scale space,” Journal of Neurocomputing, doi:10.1016/j.neucom.2006.10.072, 7 pages, 2006.
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Karim G. Oweiss