Research Interests
My research is focused on terminal nerve's function, particularly the modulatory effect that the peptides present in the terminal nerve have on the olfactory epithelium in different behavior contexts.
My research experience includes:
- Electrophysiology of olfactory system (patch clamp, electro-olfactogram, calcium imaging)
- Immunohistochemical analysis (enzyme immunohistochemistry; immunofluorescence) of the distribution and neuroanatomical localization of some neuropeptides and receptors (Myostatin, GnRH, FMRFamide, NPY) in the brain of animals (fish, amphibians) in different developmental stages.
- Tracer application (HRP, DiI, DiO, biocytin) in the olfactory pit and brain of amphibians and fish.
- Surgical olfactory placodectomy in toads, frogs and lungfish.
- Transplantation of placodal cell groups.
Selected Publications
Mousley A, Polese G, Marks NJ, Eisthen HL. 2006. Terminal nerve- derived neuropeptide y modulates physiological responses in the
olfactory epithelium of hungry axolotls (Ambystoma mexicanum). J
Neurosci. Jul 19;26(29):7707-17.
Eisthen LH, Polese G. 2006. Vertebrate Olfactory Subsystems and their
Evolution. The Evolution of Nervous Systems in Non-Mammalian
Vertebrates. Elsevier. Chapter 10, vol 3.
Pinelli C, D'Aniello B, Polese G, Rastogi RK. 2004. Extrabulbar
olfactory system and nervus terminalis FMRFamide immunoreactive
components in Xenopus laevis ontogenesis. J Chem Neuroanat. Sep;28 (1-2):37-46.
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Gianluca
Polese 